Cartilage Wear in Healthy and Osteoarthritis Joints

This study is designed to determine whether the outermost layer of articular cartilage deficient in Osteoarthritis (OA). Phospholipids present healthy and osteoarthritis (OA) synovial fluid show significant differences their concentration. While examining surface properties OA joints, we found that PLs molecules cannot support lubrication, increased friction was observed. Our lubrication mechanism based on a active phospholipids (SAPL) multibilayer which condition deactivated removed from under conditions. Cartilage wettability clearly demonstrated decrease hydrophobicity, contact angle, θ (theta), dropping 103° bovine 65° partially depleted 35.1° for completely surface. These results are discussed context phospholipid lubricin, each has specific roles lamellar-repulsive system. However, major indicator wear (model) introduced this study.